Inhibition of Connexin43 gap junctional com- munication by G(q)-coupled receptors: a critical role for residue Tyr265
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Acute loss of Cell–Cell Communication Caused by G Protein–coupled Receptors: A Critical Role for c-Src
Gap junctions mediate cell-cell communication in almost all tissues, but little is known about their regulation by physiological stimuli. Using a novel single-electrode technique, together with dye coupling studies, we show that in cells expressing gap junction protein connexin43, cell-cell communication is rapidly disrupted by G protein-coupled receptor agonists, notably lysophosphatidic acid,...
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